Autophagy Reduces the Degradation and Promotes Membrane Localization of Occludin to Enhance the Intestinal Epithelial Tight Junction Barrier against Paracellular Macromolecule Flux - Concepedia

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Autophagy Reduces the Degradation and Promotes Membrane Localization of Occludin to Enhance the Intestinal Epithelial Tight Junction Barrier against Paracellular Macromolecule Flux

DOI Full Paper Access

53

Citations

48

References

2022

Year

Kushal Saha, Ashwinkumar Subramenium Ganapathy, Alexandra Wang, Nathan M. Morris, Eric Suchanec, Wei Ding, Gregory S. Yochum, Walter A. Koltun, Meghali Nighot, Thomas Ma,

Journal of Crohn s and Colitis

Abstract

Our data suggest a novel role of autophagy in promoting the intestinal TJ barrier by increasing occludin levels in an ERK1/2 mitogen-activated protein kinase-dependent mechanism.

References

	Year	Citations

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