Concepedia

Publication | Open Access

Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

DOIFull Paper Access

24

Citations

45

References

2022

Year

Anna Borgenvik, Karl O. Holmberg, Sara Bolin, Miao Zhao, Vasil Savov, Gabriela Rosén, Sonja Hutter, Alexandra Garancher, Aldwin Suryo Rahmanto, Tobias Bergström,
Cancer Research

Abstract

SOX9 facilitates therapy escape and recurrence in medulloblastoma via temporal inhibition of MYC/MYCN genes, revealing a strategy to specifically target SOX9-positive cells to prevent tumor relapse.

References

YearCitations

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