HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC- Driven Medulloblastoma

Yanxin Pei, Kun-Wei Liu, Jun Wang, +21

Cancer Cell

Myc- Driven MedulloblastomaMalignant DiseaseOncogenic AgentPi3k Antagonists CooperateMedicine +7

Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis

Zhe Zhu, Pinar Mesci, Jean Bernatchez, +31

Cell stem cell

GliomaViral PathogenesisImmunologyVirologySox2-integrin αVβ5 Axis +4

A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases

Livia Garzia, Noriyuki Kijima, A. Sorana Morrissy, +49

Cell

Neuro-oncologyTumoral PathologySurgical PathologyHematologyPathology +2

Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma

Kent Riemondy, Sujatha Venkataraman, Nicholas Willard, +18

Neuro-Oncology

Childhood Mb SubgroupsImmunogeneticsFunctional GenomicsImmune Cell SubpopulationsTumor Heterogeneity +13

Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma

Catherine Lee, Vasilisa A. Rudneva, Serap Erkek, +14

Nature Communications

NRL and CRX Define Photoreceptor Identity and Reveal Subgroup-Specific Dependencies in Medulloblastoma

Alexandra Garancher, Charles Lin, Morgane Morabito, +24

Cancer Cell

BiologyPhotoreceptor CellMedicineGeneticsMolecular Genetics +3

Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

Matko Čančer, Sonja Hutter, Karl O. Holmberg, +10

Cell stem cell

Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma

Jessica M. Rusert, Edwin F. Juarez, Sebastian Brabetz, +37

Cancer Research

Neuro-oncologyPediatric Brain TumorsDifferent TherapiesSimilar TherapiesTumor Heterogeneity +12

GSK3-mediated MAF phosphorylation in multiple myeloma as a potential therapeutic target

Nirmitha I. Herath, Nathalie Rocques, Alexandra Garancher, +2

Blood Cancer Journal

RAF proteins exert both specific and compensatory functions during tumour progression of NRAS-driven melanoma

Coralie Dorard, Charlène Estrada, Céline Barbotin, +9

Nature Communications