Integrated single-cell analysis-based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis

Abstract

We refined the nomenclature of mononuclear phagocytes in mouse atherosclerotic vessels, and show conserved transcriptomic features of macrophages and DCs in atherosclerosis in mice and humans, emphasizing the relevance of mouse models to study mononuclear phagocytes in atherosclerosis.