Tumori Journal · 1967 · 31 citations · 18 references
Epigenetic ChangeGeneticsDna MethylationMolecular BiologyTumoral Growth RateUnfractioned T-rnasEpigeneticsNeuro-oncologyAtypia DegreeLong Non-coding RnaRadiation OncologyRna BiologyBrain TumorsDna DemethylationGene ExpressionChromatinDevelopmental BiologyNatural SciencesEpigenomicsMedicineNon-coding Rna
In unfractioned t-RNAs, prepared from cerebral tumors, the methylated bases were found in a high amount. The increase of them is proportional to the atypia degree, but it is not related to the tumoral growth rate. The results are discussed, in relation to the carcinogenetic hypothesis of the overmethylation.
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Structure of a Ribonucleic Acid
Robert W. Holley, Jean Apgar, George A. Everett et al. · Science · 1965 · 1.4K citations