“In vitro” Antimycotic Activity of Fenticonazole (Rec 15/1476): Die antimykotische Wirkung von Fenticonazole (Rec 15/1476)

Abstract

Summary: The “in vitro” activity of Fenticonazole (Rec 15/1476) against a large variety of wild and collection fungi, in comparison with some trade drugs, was studied. The fungistatic and fungicidal activity of Fenticonazole was also studied against a certain number of yeasts variing the pH of the medium. The results of the “in vitro” tests have demonstrated good activity of Fenticonazole against dermatophytes and against fungi responsible for deep infections. The activity of Fenticonazole against yeasts is very good at acid pH while it decreases at alkaline pH. Zusammenfassung: Die “invitro” Wirksamkeit von Fenticonazole (Rec 15/1476) gegen ver‐schieden pathogene Pilze wurde untersucht. Das Spektrum der fungiziden Wirkung ist sehr breit: Dermatophyten, Hefen und dimorphe Pilze werden stark gehemmt. Fenticonazole zeigt “in vitro” die hwöchste Wirkung gegen hefen bei pH 4–5.