Concepedia

Metformin mitigates cholesterol accumulation via the AMPK/SIRT1 pathway to protect osteoarthritis chondrocytes

Hengte Xing, ChuanCai Liang, Chenyu Wang, Xiongfeng Xu, Yong Hu, Bo Qiu

Biochemical and Biophysical Research Communications · 2022 · 23 citations · 28 references

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References

28

Osteoarthritis is a serious disease.

Gillian Hawker · PubMed · 2019 · 386 citations

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The CH25H–CYP7B1–RORα axis of cholesterol metabolism regulates osteoarthritis

Wan-Su Choi, Gyuseok Lee, Won‐Hyun Song et al. · Nature · 2019 · 333 citations

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Metformin limits osteoarthritis development and progression through activation of AMPK signalling

Jun Li, Bin Zhang, Wei‐Xiao Liu et al. · Annals of the Rheumatic Diseases · 2020 · 304 citations · Full text

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Pretreatment with Tilianin improves mitochondrial energy metabolism and oxidative stress in rats with myocardial ischemia/reperfusion injury via AMPK/SIRT1/PGC-1 alpha signaling pathway

Tian Li, Wenjiang Cao, Rujing Yue et al. · Journal of Pharmacological Sciences · 2019 · 261 citations · Full text

, , +17

Novel osmotin inhibits SREBP2 via the AdipoR1/AMPK/SIRT1 pathway to improve Alzheimer’s disease neuropathological deficits

Sonia Shah, Gayoung Yoon, Seungsoo Chung et al. · Molecular Psychiatry · 2016 · 210 citations · Full text

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