Journal of Virology · 2022 · 30 citations · 53 references
Life SciencesInfectious DiseasesMolecular BiologyHost-pathogen InteractionsMolecular VirologyVirologyViral AttachmentViral EntryViral InfectionsViral PathogenesisVirus EntryVirus-host InteractionsCell-to-cell SpreadLysosome PathwayLysosome-dependent Protein DegradationViral Envelope GlycoproteinsViral Fusion ProteinsViral GlycoproteinsVirus-host Protein InteractionsVirus-host Receptor Interactions
, Δfurin PRV virulence was significantly attenuated in mice. Therefore, NRP1 is an important host factor for PRV, and NRP1 may be a potential target for antiviral drug development.
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