Concepedia

Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase

Sergio H. Szajnman, Guadalupe García Liñares, Zhu-Hong Li, Cuiying Jiang, Melina Galizzi, Esteban J. Bontempi, Marcela Ferella, Silvia N.J. Moreno, Roberto Docampo, Juan B. Rodríguez

Bioorganic & Medicinal Chemistry · 2007 · 48 citations · 1 references

Open access

Concepts

PharmacyBiochemistryMedicinal ChemistryDrug DesignDrug DiscoverySynthetic Medicinal ChemistryEnzyme InhibitionBiological Evaluation ReportFarnesyl Diphosphate SynthaseTrypanosoma Cruzi InfectionTrypanosomatid-host InteractionsTrypanosome Infections

References

1

[16] Eukaryotic prenyltransferases

Hans C. Rilling · Methods in enzymology on CD-ROM/Methods in enzymology · 1985 · 58 citations