Critical Care Medicine · 2002 · 244 citations · 94 references
Life SciencesMolecular BiologyPharmacologyCell SignalingGene ExpressionSignal TransductionInflammatory Cell SignalingInflammatory SignalingNf-κb SignalingNuclear Factor Kappa B ActivationNuclear Factor Kappa B Signaling
From the Laboratory of Gene Regulation and Signal Transduction, the Department of Pharmacology, University of California, San Diego, La Jolla, CA. Although there are still years of intensive work ahead of us, the IKK/NF-κB pathway is a promising and important star on the intensive care horizon. Present address of Dr. Senftleben: Clinic of Anesthesiology, University of Ulm, Steinhövelstr. 9, 89075 Ulm, Germany. Address requests for reprints to: Michael Karin, PhD, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0636. E-mail: [email protected]
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Activators and target genes of Rel/NF-κB transcription factors
Heike L. Pahl · Oncogene · 1999 · 3.7K citations
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Patrick A. Baeuerle, David Baltimore · Science · 1988 · 2.2K citations
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
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