Concepedia

Publication | Open Access

Sustained Aurora Kinase B Expression Confers Resistance to PI3K Inhibition in Head and Neck Squamous Cell Carcinoma

DOIFull Paper Access

11

Citations

40

References

2022

Year

Pooja A. Shah, Vaishnavi Sambandam, Anne M. Fernandez, Hongyun Zhao, Tuhina Mazumdar, Li Shen, Qi Wang, Kazi Mokim Ahmed, Soma Ghosh, Mitchell J. Frederick,
Cancer Research

Abstract

Aurora B signaling facilitates resistance to PI3K inhibition in head and neck squamous cell carcinoma, suggesting that combined inhibition of PI3K and Aurora kinase is a rational therapeutic strategy to overcome resistance.

References

YearCitations

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