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Design, synthesis, and molecular docking of novel pyrazole-chalcone analogs of lonazolac as 5-LOX, iNOS and tubulin polymerization inhibitors with potential anticancer and anti-inflammatory activities

Medicinal ChemistryPolymer-drug ConjugateMedicinePharmacologyTubulin Polymerization InhibitorsNovel Pyrazole-chalcone AnalogsPharmacotherapyAnti-cancer AgentDrug DevelopmentMolecular DockingBiomolecular EngineeringDrug Discovery