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Publication | Open Access

Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy

DOIFull Paper Access

16

Citations

29

References

2022

Year

Lars Guelen, Thierry Fischmann, Jerelyn Wong, Smita Mauze, Marco Guadagnoli, Nikolina Bąbała, Jozef Wagenaars, Veronica Juan, David B. Rosen, Winnie Prosise,
Journal for ImmunoTherapy of Cancer

Abstract

MK-5890 is a novel CD27 agonistic antibody with the potential to complement the activity of PD-1 checkpoint inhibition in cancer immunotherapy and is currently undergoing clinical evaluation.

References

YearCitations

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