Concepedia

Highly Potent and Selective Dopamine D<sub>4</sub> Receptor Antagonists Potentially Useful for the Treatment of Glioblastoma

Pegi Pavletić, Ana Semeano, Hideaki Yano, Alessandro Bonifazi, Gianfabio Giorgioni, Alessandro Piergentili, Wilma Quaglia, Maria Giovanna Sabbieti, Dimitrios Agas, Giorgio Santoni,

Journal of Medicinal Chemistry · 2022 · 17 citations · 38 references

DOIFull text

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Concepts

Abstract

induced an increased effect in reducing the cell viability with respect to temozolomide, which is the first-choice chemotherapeutic drug in GBM.

References

38

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

Antoine Daina, Olivier Michielin, Vincent Zoete · Scientific Reports · 2017 · 17.1K citations · Full text

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Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells

Lucia Ricci‐Vitiani, Roberto Pallini, Mauro Biffoni et al. · Nature · 2010 · 1.4K citations

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Empirical Scoring Functions for Advanced Protein−Ligand Docking with PLANTS

Oliver Korb, Thomas Stützle, Thomas E. Exner · Journal of Chemical Information and Modeling · 2009 · 1.3K citations

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Multiple dopamine D4 receptor variants in the human population

Hubert H.M. Van Tol, Caren M. Wu, Hong‐Chang Guan et al. · Nature · 1992 · 967 citations

, , +11

Modulation of Intracellular Cyclic AMP Levels by Different Human Dopamine D4 Receptor Variants

Vida Asghari, Suparna Sanyal, Saskia Buchwaldt et al. · Journal of Neurochemistry · 1995 · 862 citations

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