Concepedia

Uniform soluble support for the large-scale synthesis of sequence-defined macromolecules

Irene De Franceschi, Chiel Mertens, Nezha Badi, Filip Du Prez

Polymer Chemistry · 2022 · 19 citations · 41 references

Concepts

Combinatorial ChemistryMonodisperse Soluble SupportEngineeringBiochemistrySingle PeakNatural SciencesPeptide LibraryMass SpectrometryMolecular BiologySynthetic BiologyPeptide SynthesisAnalytical ChemistryUniform Soluble SupportPrecision MacromoleculeBiomolecular EngineeringMolecular Design

Abstract

A monodisperse soluble support is used as an effective tool for the large-scale, liquid-phase synthesis of sequence-defined macromolecules. This uniform support allows for direct characterisation and leads to a single peak in mass spectrometry.

References

41

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Peptide Engineering, Altmetric Attention Score, Peptide Science +20

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Synthetic Macromolecule, Precise Macromolecular Synthesis, Engineering +10

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Biochemistry, Natural Sciences, Peptide Engineering +7

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Synthetic Macromolecule, Engineering, Depolymerization +13

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Biochemistry, Peptide Engineering, Peptide Library +3