IL4I1 enhances PD-L1 expression through JAK/STAT signaling pathway in lung adenocarcinoma

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

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A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma

Alexander C. Huang, Robert Orlowski, Xiaowei Xu et al. · Nature Medicine · 2019 · 702 citations

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Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patients with EGFR Mutation

Nan Chen, Wenfeng Fang, Jianhua Zhan et al. · Journal of Thoracic Oncology · 2015 · 686 citations · Full text

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IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression

Ahmed Sadik, Luis F. Somarribas Patterson, Selcen Öztürk et al. · Cell · 2020 · 576 citations · Full text

Medicine, Immunology, Oncology +16

<scp>PD</scp>‐L1 expression is mainly regulated by interferon gamma associated with <scp>JAK</scp>‐<scp>STAT</scp> pathway in gastric cancer

Kousaku Mimura, Jun Liang Teh, Hirokazu Okayama et al. · Cancer Science · 2017 · 323 citations · Full text

Life Sciences, Immunology, Oncology +16