Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility

The UK Biobank resource with deep phenotyping and genomic data

Clare Bycroft, Colin Freeman, Desislava Petkova et al. · Nature · 2018 · 9.7K citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

NF-κB signaling in inflammation

Ting Liu, Lingyun Zhang, Donghyun Joo et al. · Signal Transduction and Targeted Therapy · 2017 · 8.1K citations · Full text

Life Sciences, Immunology, Pathology +17

The support of human genetic evidence for approved drug indications

Matthew R. Nelson, Hannah Tipney, Jeffery L. Painter et al. · Nature Genetics · 2015 · 1.8K citations

Medicine, Genetics, Molecular Genetics +10

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

John D. Rioux, Ramnik J. Xavier, Kent D. Taylor et al. · Nature Genetics · 2007 · 1.8K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

Wei Zhou, Jonas B. Nielsen, Lars G. Fritsche et al. · Nature Genetics · 2018 · 1.6K citations

Public Health, Biostatistics, Genetics +14