Seneca Valley Virus Induces DHX30 Cleavage to Antagonize Its Antiviral Effects

Wei Wen, Zixuan Zheng, Haoyuan Wang, Qiongqiong Zhao, Mengge Yin, Huanchun Chen, Xiangmin Li, Ping Qian

Journal of Virology · 2022 · 15 citations · 32 references

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Concepts

Abstract

DHX30, an RNA helicase, is identified as a 3C pro -interacting protein regulating Seneca Valley virus (SVV) replication dependent on its helicase activity. DHX30 functioned as a viral-RNA binding protein that inhibited SVV replication at the early stage of virus infection.

References

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