Serotonin 5-HT7 receptor is a biomarker poor prognostic factor and induces proliferation of triple-negative breast cancer cells through FOXM1

Characterization of SB‐269970‐A, a selective 5‐HT₇ receptor antagonist

Jim J. Hagan, Gary Price, Nigel Deeks et al. · British Journal of Pharmacology · 2000 · 285 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Tryptophan hydroxylase 1 and 5-HT7 receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin signaling

Jaya Gautam, Suhrid Banskota, Sushil Chandra Regmi et al. · Molecular Cancer · 2016 · 128 citations · Full text

Medicine, Oncology, Pharmacology +17

Targeted Silencing of Elongation Factor 2 Kinase Suppresses Growth and Sensitizes Tumors to Doxorubicin in an Orthotopic Model of Breast Cancer

İbrahim Tekedereli, S. Neslihan Alpay, Clint D.J. Tavares et al. · PLoS ONE · 2012 · 118 citations · Full text

Life Sciences, Oncology, Pharmacology +17

FOXM1 regulates expression of eukaryotic elongation factor 2 kinase and promotes proliferation, invasion and tumorgenesis of human triple negative breast cancer cells

Zühal Hamurcu, Ahmed A. Ashour, Nermin Kahraman et al. · Oncotarget · 2016 · 114 citations · Full text

Life Sciences, Molecular Biology, Oncology +12

Serotonin activates glycolysis and mitochondria biogenesis in human breast cancer cells through activation of the Jak1/STAT3/ERK1/2 and adenylate cyclase/PKA, respectively

Mauro Sola‐Penna, Larissa Pereira Paixão, Jéssica Ristow Branco et al. · British Journal of Cancer · 2019 · 104 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17