Concepedia

TM4SF19-AS1 facilitates the proliferation of lung squamous cell carcinoma by recruiting WDR5 to mediate TM4SF19

Machang Luo, Lingyan Xie, Yonghua Su, Kaijun Zhang, Rongzhang Liang, Zhiyi Ma, Youtang Li

Molecular and Cellular Probes · 2022 · 15 citations · 19 references

DOIFull text

Open access

Abstract

Our research demonstrated that TM4SF19-AS1 affected LSCC cell proliferation by recruiting WDR5 to manipulate transmembrane-4-lsix-family-member-19 (TM4SF19), which offers a new observation on LSCC pathogenesis, indicating that TM4SF19-AS1 is able to be a promising target for LSCC treatment.

References

19

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

Yul W. Yang, Amartya Sanyal, M. Ryan Corces et al. · Nature · 2011 · 2K citations · Full text

, , +16

LncRNA SATB2-AS1 inhibits tumor metastasis and affects the tumor immune cell microenvironment in colorectal cancer by regulating SATB2

Mu Xu, Xueni Xu, Bei Pan et al. · Molecular Cancer · 2019 · 331 citations · Full text

lncRNA MEG3 inhibit proliferation and metastasis of gastric cancer via p53 signaling pathway.

Wei Gh, X Wang · PubMed · 2017 · 285 citations

lncRNA HOXD-AS1 Regulates Proliferation and Chemo-Resistance of Castration-Resistant Prostate Cancer via Recruiting WDR5

Peng Gu, Xu Chen, Ruihui Xie et al. · Molecular Therapy · 2017 · 211 citations · Full text

Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency

Yul W. Yang, Ryan A. Flynn, Yong Chen et al. · eLife · 2014 · 202 citations · Full text

, , +18