A defined heat pretreatment of gelatin enables control of hydrolytic stability, stiffness, and microstructural architecture of fibrin–gelatin hydrogel blends

Abstract

The stiffness, microstructure, and swelling of long-term stable fibrin–gelatin hydrogels with support of endothelial cell growth can be controlled due to defined heat pretreatment of gelatin, which results in tailored molecular weight distributions.