Ginsenoside Rg5 allosterically interacts with P2RY12 and ameliorates deep venous thrombosis by counteracting neutrophil NETosis and inflammatory response - Concepedia

Concepedia

Publication | Open Access

Ginsenoside Rg5 allosterically interacts with P2RY12 and ameliorates deep venous thrombosis by counteracting neutrophil NETosis and inflammatory response

DOI Full Paper Access

27

Citations

42

References

2022

Year

Ziyu Chen, Gaorui Wang, Xueqing Xie, Heng Liu, Jun Liao, Hailian Shi, Min Chen, Shusheng Lai, Zhengtao Wang, Xiaojun Wu

Frontiers in Immunology

Abstract

Rg5 could attenuate experimental DVT by counteracting NETosis and inflammatory response in neutrophils <i>via</i> P2RY<sub>12</sub>, which may pave the road for its clinical application in the prevention of DVT-related disorders.

References

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