Development of 5-FU-modified tumor suppressor microRNAs as a platform for novel microRNA-based cancer therapeutics

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

Rosalind C. Lee, Rhonda Feinbaum, Victor Ambros · Cell · 1993 · 12.8K citations · Full text

Life Sciences, Genetics, Molecular Genetics +7

Frequent deletions and down-regulation of micro- RNA genes <i>miR15</i> and <i>miR16</i> at 13q14 in chronic lymphocytic leukemia

George A. Calin, Calin Dan Dumitru, Masayoshi Shimizu et al. · Proceedings of the National Academy of Sciences · 2002 · 5K citations · Full text

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Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

Bruce Wightman, Ilho Ha, Gary Ruvkun · Cell · 1993 · 4.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +11

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

Philip A. Gregory, Andrew G. Bert, Emily Paterson et al. · Nature Cell Biology · 2008 · 3.9K citations

Life Sciences, Cell Biology, Molecular Biology +14

RAS Is Regulated by the let-7 MicroRNA Family

Steven Johnson, Jaclyn Shingara, Mike Byrom et al. · Cell · 2005 · 3.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +9