Ketamine induces rapid antidepressant effects via the autophagy-NLRP3 inflammasome pathway

Ketamine blocks bursting in the lateral habenula to rapidly relieve depression

Yan Yang, Yihui Cui, Kangning Sang et al. · Nature · 2018 · 1.1K citations

Medicine, Neurobiology, Neuroscience +10

Sucrose preference test for measurement of stress-induced anhedonia in mice

Mengying Liu, Chunyu Yin, Li‐Juan Zhu et al. · Nature Protocols · 2018 · 1K citations

Veterinary Medicine, Behavioral Sciences, Neuroscience +6

NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder

Elísabet Alcocer‐Gómez, N. Casas Barquero, Jéssica Núñez‐Vasco et al. · Brain Behavior and Immunity · 2013 · 445 citations · Full text

Life Sciences, Immunology, Psychiatry +13

Microglial NLRP3 inflammasome activation mediates IL-1β-related inflammation in prefrontal cortex of depressive rats

Ying Pan, Xu-Yang Chen, Qingyu Zhang et al. · Brain Behavior and Immunity · 2014 · 401 citations

Life Sciences, Immunology, Neuroscience +16

Melatonin prevents neuroinflammation and relieves depression by attenuating autophagy impairment through FOXO3a regulation

Tahir Ali, Shafiq Ur Rahman, Weifen Li et al. · Journal of Pineal Research · 2020 · 324 citations

Life Sciences, Neurobiology, Neuroscience +17