Inhibition of PTPN21 has antitumor effects in glioma by restraining the EGFR/PI3K/AKT pathway

Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex

Dos D. Sarbassov, David A. Guertin, Siraj M. Ali et al. · Science · 2005 · 6.2K citations

Life Sciences, Cell Biology, Molecular Biology +17

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2014–2018

Quinn T. Ostrom, Gino Cioffi, Kristin Waite et al. · Neuro-Oncology · 2021 · 2.6K citations · Full text

Medicine, Neurology, Oncology +15

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity.

Ryo Nishikawa, Xiang-Dong Ji, R. Christopher Harmon et al. · Proceedings of the National Academy of Sciences · 1994 · 931 citations

Medicine, Molecular Biology, Oncology +17

Temozolomide: Mechanisms of Action, Repair and Resistance

Jihong Zhang, Malcolm F. G. Stevens, Tracey D. Bradshaw · Current Molecular Pharmacology · 2011 · 889 citations

Medicine, Oncology, Pharmacology +17

Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response

Nicholas J. Szerlip, Alicia Pedraza, Debyani Chakravarty et al. · Proceedings of the National Academy of Sciences · 2012 · 542 citations · Full text

Medicine, Cancer Biology, Oncology +17