STRIPE3, encoding a human dNTPase SAMHD1 homolog, regulates chloroplast development in rice

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

Nadine Laguette, Bijan Sobhian, Nicoletta Casartelli et al. · Nature · 2011 · 1.5K citations

Life Sciences, Immunology, Infectious Diseases +12

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

Kasia Hrecka, Caili Hao, Magda Gierszewska et al. · Nature · 2011 · 1.2K citations

Life Sciences, Immunology, Molecular Biology +9

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

David C. Goldstone, Valerie Ennis-Adeniran, Joseph J. Hedden et al. · Nature · 2011 · 828 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

Gillian Rice, Jacquelyn Bond, Aruna Asipu et al. · Nature Genetics · 2009 · 684 citations

Life Sciences, Genetics, Molecular Genetics +11

The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells

Elisa Franzolin, Giovanna Pontarin, Chiara Rampazzo et al. · Proceedings of the National Academy of Sciences · 2013 · 272 citations · Full text

Life Sciences, Genetics, Molecular Biology +14