Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love, Wolfgang Huber, Simon Anders

Genome biology

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

Guangchuang Yu, Li-Gen Wang, Yanyan Han, +1

OMICS A Journal of Integrative Biology

GeneticsGenomicsGene RecognitionBioinformatics DatabaseR Package +22

Near-optimal probabilistic RNA-seq quantification

Nicolas Bray, Harold Pimentel, Páll Melsted, +1

Nature Biotechnology

Functional GenomicsEngineeringGeneticsRna Structure PredictionComputational Biology +5

MultiQC: summarize analysis results for multiple tools and samples in a single report

Philip Ewels, Måns Magnusson, Sverker Lundin, +1

Bioinformatics

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

Steffen Durinck, Paul T. Spellman, Ewan Birney, +1

Nature Protocols

Functional GenomicsEngineeringMolecular EcologyR/bioconductor Package BiomartOmics Datasets +13

BioMart and Bioconductor: a powerful link between biological databases and microarray data analysis

Steffen Durinck, Yves Moreau, A. Kasprzyk, +4

Computer applications in the biosciences

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

Akinori Takaoka, Zhichao Wang, Myoung Kwon Choi, +9

Nature

Molecular ImmunologyInnate Immune SystemImmunologyInnate Immune ResponseCytosolic Dna Sensor +3

Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis

Andrew Oberst, Christopher P. Dillon, Ricardo Weinlich, +6

Nature

InflammationSignal TransductionSignaling PathwayMedicineApoptosis +7

Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally

Eugene Varfolomeev, Marcus Schuchmann, Victor Luria, +15

Immunity

InflammationKnockout MouseSignal TransductionTnf ReceptorsSignaling Pathway +10

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand, +20

Immunity

Protein FunctionSignal TransductionMedicineNatural SciencesApoptosis +12