Concepedia

Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis

Qian Zhang, Piao Luo, Fei Xia, Huan Tang, Jiayun Chen, Junzhe Zhang, Dandan Liu, Yongping Zhu, Yanqing Liu, Liwei Gu,

Cell chemical biology · 2022 · 120 citations · 28 references

DOI

Concepts

References

28

The capsaicin receptor: a heat-activated ion channel in the pain pathway

Michael J. Caterina, Mark Schumacher, Makoto Tominaga et al. · Nature · 1997 · 9.1K citations

, , +16

Immunodesign of experimental sepsis by cecal ligation and puncture

Daniel Rittirsch, Markus Huber‐Lang, Michael A. Flierl et al. · Nature Protocols · 2008 · 2.2K citations · Full text

, , +12

Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages

Wai‐Ki Ip, Namiko Hoshi, Dror S. Shouval et al. · Science · 2017 · 1.4K citations · Full text

, , +17

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

Eva M. Pålsson‐McDermott, Annie M. Curtis, Gautam Goel et al. · Cell Metabolism · 2015 · 1.4K citations · Full text

, , +16

The Metabolism of Carcinoma Cells

Otto Warbürg · The Journal of Cancer Research · 1925 · 976 citations · Full text

, , +4