Concepedia

Network Pharmacology and Bioinformatics Methods Reveal the Mechanism of Berberine in the Treatment of Ischaemic Stroke

Ke Song, Yikun Sun, Haoqi Liu, Yuanyuan Li, Na An, Liqin Wang, Hanlai Zhang, Fan Yang, Yanwei Xing, Yonghong Gao

Evidence-based Complementary and Alternative Medicine · 2022 · 13 citations · 74 references

DOIFull text

Open access

Abstract

The potential targets and biological effects of berberine in the treatment of ischaemic stroke were predicted in this study. The lncRNA H19/EGFR/JNK1/c-Jun signalling pathway may be a key mechanism of berberine-induced neuroprotection in ischaemic stroke.

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