Induction of GLI1 by miR-27b-3p/FBXW7/KLF5 pathway contributes to pulmonary arterial hypertension

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

Matthias Lauth, Åsa Bergström, Takashi Shimokawa et al. · Proceedings of the National Academy of Sciences · 2007 · 779 citations · Full text

Medicine, Oncology, Pharmacology +15

ETA and ETB Receptors Modulate the Proliferation of Human Pulmonary Artery Smooth Muscle Cells

Neil Davie, STEPHEN J. HALEEN, Paul D. Upton et al. · American Journal of Respiratory and Critical Care Medicine · 2002 · 309 citations

Life Sciences, Pharmacology, Physiology +11

miRNA-27b Targets Vascular Endothelial Growth Factor C to Inhibit Tumor Progression and Angiogenesis in Colorectal Cancer

Jun Ye, Xianguo Wu, Dang Wu et al. · PLoS ONE · 2013 · 172 citations · Full text

Medicine, Molecular Biology, Oncology +17

The Fbw7 Tumor Suppressor Targets KLF5 for Ubiquitin-Mediated Degradation and Suppresses Breast Cell Proliferation

Dong Zhao, Hanqiu Zheng, Zhongmei Zhou et al. · Cancer Research · 2010 · 148 citations

Life Sciences, Molecular Biology, Oncology +15

Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma Cells

Tapati Mazumdar, Jennifer DeVecchio, Akwasi Agyeman et al. · Cancer Research · 2011 · 132 citations

Life Sciences, Cancer Biology, Oncology +17