Concepedia

Gasdermin D is involved in switching from apoptosis to pyroptosis in TLR4-mediated renal tubular epithelial cells injury in diabetic kidney disease

Shuguang Yuan, Youliang Wang, Zheng Li, Xiaojun Chen, Panai Song, Anqun Chen, Zhong Qu, Wen Si, Hong Liu, Xuejing Zhu

Archives of Biochemistry and Biophysics · 2022 · 29 citations · 21 references

DOI

Concepts

References

21

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature · 2015 · 6.5K citations

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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Nobuhiko Kayagaki, Irma B. Stowe, Bettina L. Lee et al. · Nature · 2015 · 3.7K citations

, , +13

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

Xing Liu, Zhibin Zhang, Jianbin Ruan et al. · Nature · 2016 · 3.2K citations · Full text

, , +9

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

Yupeng Wang, Wenqing Gao, Xuyan Shi et al. · Nature · 2017 · 3.2K citations

, , +13

Pore-forming activity and structural autoinhibition of the gasdermin family

Jingjin Ding, Kun Wang, Wang Liu et al. · Nature · 2016 · 2.8K citations

, , +8