Concepedia

Structure of a 14-3-3ε:FOXO3a<sup>pS253</sup> Phosphopeptide Complex Reveals 14-3-3 Isoform-Specific Binding of Forkhead Box Class O Transcription Factor (FOXO) Phosphoproteins

S. Mathivanan, Puneeth Kumar Chunchagatta Lakshman, Manvi Singh, Saranya Giridharan, Keerthana Sathish, Manjunath A. Hurakadli, Kavitha Bharatham, Neelagandan Kamariah

ACS Omega · 2022 · 16 citations · 34 references

DOIFull text

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Concepts

Abstract

, providing a framework for the rational design of isoform-specific FOXO/14-3-3 protein-protein interaction inhibitors for therapy.

References

34

VMD: Visual molecular dynamics

William Humphrey, Andrew Dalke, Klaus Schulten · Journal of Molecular Graphics · 1996 · 66.6K citations

, , +12

<i>Coot</i>: model-building tools for molecular graphics

Paul Emsley, Kevin Cowtan · Acta Crystallographica Section D Biological Crystallography · 2004 · 31.4K citations · Full text

, , +17

<i>Phaser</i>crystallographic software

Airlie J. McCoy, Ralf W. Grosse‐Kunstleve, Paul D. Adams et al. · Journal of Applied Crystallography · 2007 · 20.9K citations · Full text

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The CCP4 suite: programs for protein crystallography

Number Collaborative Computational Project · Acta Crystallographica Section D Biological Crystallography · 1994 · 17.3K citations

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Overview of the<i>CCP</i>4 suite and current developments

Martyn Winn, Charles Ballard, Kevin Cowtan et al. · Acta Crystallographica Section D Biological Crystallography · 2011 · 12.6K citations · Full text

, , +16