Concepedia

FKBP11 rewires UPR signaling to promote glucose homeostasis in type 2 diabetes and obesity

Hilde Herrema, Dongxian Guan, Jae Won Choi, Xudong Feng, Mario Andrés Salazar Hernández, Farhana Faruk, Thomas Auen, Eliza Boudett, Rongya Tao, Hyonho Chun,

Cell Metabolism · 2022 · 39 citations · 64 references

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64

XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

Hiderou Yoshida, Toshie Matsui, Akira Yamamoto et al. · Cell · 2001 · 4.1K citations · Full text

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Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes

Umut Özcan, Qiong Cao, Erkan Yılmaz et al. · Science · 2004 · 3.8K citations

, , +17

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

Heather P. Harding, Yuhong Zhang, David Ron · Nature · 1999 · 3.3K citations

, , +10

THE MAMMALIAN UNFOLDED PROTEIN RESPONSE

Martin Schröder, Randal J. Kaufman · Annual Review of Biochemistry · 2005 · 3K citations · Full text

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Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1

Fumihiko Urano, Xiao-Zhong Wang, Anne Bertolotti et al. · Science · 2000 · 3K citations

, , +16