International Journal of Molecular Sciences · 2022 · 13 citations · 39 references
Natural SciencesMaterials EngineeringMaterials ScienceBiocompatibilityBiomaterialsBiomechanicsTechnical TextilesTextile MaterialsBiomedical ApplicationsBlood CompatibilityComposite Mechanical PropertiesCrystalline StructureMoistureNonwoven FabricsNonwoven MaterialsSilk Biomaterials
Silk is a naturally occurring material and has been widely used in biomedical and cosmetic applications owing to its unique properties, including blood compatibility, excellent cytocompatibility, and a low inflammatory response in the body. A natural silk nonwoven fabric with good mechanical properties was recently developed using the binding property of sericin. In this study, silk/rayon composite nonwoven fabrics were developed to increase productivity and decrease production costs, and the effect of the silk/rayon composition on the structure and properties of the fabric was examined. The crystalline structure of silk and rayon was maintained in the fabric. As the silk content increased, the porosity and moisture regain of the silk/rayon web and nonwoven fabric decreased. As the silk content increased, the maximum stress of the web and nonwoven fabric increased, and the elongation decreased. Furthermore, the silk/rayon web exhibited the highest values of maximum stress and elongation at ~200 °C. Regardless of the silk/rayon composition, all silk/rayon nonwoven fabrics showed good cytocompatibility. Thus, the silk/rayon fabric is a promising material for cosmetic and biomedical applications owing to its diverse properties and high cell viability.
39
The inflammatory responses to silk films in vitro and in vivo
Lorenz Meinel, Sandra Hofmann, Vassilis Karageorgiou et al. · Biomaterials · 2004 · 780 citations
In vivo degradation of three-dimensional silk fibroin scaffolds
Yongzhong Wang, D. Rudym, Ashley Walsh et al. · Biomaterials · 2008 · 775 citations
Cell proliferation and migration in silk fibroin 3D scaffolds
Biman B. Mandal, Subhas C. Kundu · Biomaterials · 2009 · 573 citations