Plasma and Interstitial Fluid Pharmacokinetics of Prophylactic Cefazolin in Elective Bariatric Surgery Patients

Rochelle Ryan, Dwane Jackson, George Hopkins, Victoria Eley, Rebecca Christensen, André van Zundert, Steven C. Wallis, Jeffrey Lipman, Suzanne L. Parker, Jason A. Roberts

Antimicrobial Agents and Chemotherapy · 2022 · 17 citations · 31 references

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Abstract

Guidelines for surgical prophylactic dosing of cefazolin in bariatric surgery vary in terms of recommended dose. This study aimed to describe the plasma and interstitial fluid (ISF) cefazolin pharmacokinetics in patients undergoing bariatric surgery and to determine an optimum dosing regimen.

References

31