Performance of the Cepheid Methicillin-Resistant Staphylococcus aureus/S. aureus Skin and Soft Tissue Infection PCR Assay on Respiratory Samples from Mechanically Ventilated Patients for S. aureus Screening during the Phase 2 Double-Blind SAATELLITE Study

Alexey Ruzin, Olivier Barraud, Li Yu, Bruno François, Miguel Sánchez García, Philippe Eggimann, Pierre‐François Dequin, Pierre‐François Laterre, Vincent Huberlant, L. Viña,

Journal of Clinical Microbiology · 2022 · 11 citations · 21 references

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Abstract

We investigated the performance of the Xpert methicillin-resistant Staphylococcus aureus (MRSA)/ S. aureus skin and soft tissue (SSTI) quantitative PCR (qPCR) assay in SAATELLITE, a multicenter, double-blind, phase 2 study of suvratoxumab, a monoclonal antibody (MAb) targeting S. aureus alpha-toxin, for reducing the incidence of S. aureus pneumonia.

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