Histopathological and Epigenetic Changes in Myocardium Associated with Cancer Therapy-Related Cardiac Dysfunction

Chiyoko‐Ikeda Terada, Kenji Onoue, Tomomi Fujii, Hiroe Itami, Kohei Morita, Tomoko Uchiyama, Maiko Takeda, Hitoshi Nakagawa, Tomoya Nakano, Youichirou Baba,

ESC Heart Failure · 2022 · 13 citations · 23 references

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Abstract

Our results indicate distinct morphological characteristics in myocardial histopathology associated with CTRCD. p53 and H3K27ac histone modification could be sensitive markers of CTRCD and suggest a mechanistic involvement of epigenetic changes.

References

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