Macrophage-derived CCL23 upregulates expression of T-cell exhaustion markers in ovarian cancer

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

Tyler J. Curiel, George Coukos, Linhua Zou et al. · Nature Medicine · 2004 · 5.1K citations

Life Sciences, Immunology, Oncology +16

Determining cell type abundance and expression from bulk tissues with digital cytometry

Aaron M. Newman, Chloé B. Steen, Chih Long Liu et al. · Nature Biotechnology · 2019 · 4.9K citations

Life Sciences, Cell Biology, Molecular Biology +16

Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo

Nadine Jetten, Sanne Verbruggen, Marion J. Gijbels et al. · Angiogenesis · 2013 · 844 citations

Life Sciences, Immunology, Pathobiology +14

Exhaustion of tumor-specific CD8+ T cells in metastases from melanoma patients

Lukas Baitsch, Petra Baumgaertner, Estelle Devêvre et al. · Journal of Clinical Investigation · 2011 · 824 citations · Full text

Life Sciences, Immunology, Oncology +17

A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients

Meiying Zhang, Yifeng He, Xiangjun Sun et al. · Journal of Ovarian Research · 2014 · 548 citations · Full text

Medicine, Oncology, Pathology +17