Matrix-bound Cyr61/CCN1 is required to retain the properties of the bone marrow mesenchymal stem cell niche but is depleted with aging

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

Massimo Dominici, Katarina Le Blanc, Ingo Mueller et al. · Cytotherapy · 2006 · 17.4K citations

Regenerative Medicine, Cell Therapy, Minimal Criteria +12

The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

Joon-Il Jun, Lester F. Lau · Nature Cell Biology · 2010 · 942 citations · Full text

Inflammation, Fibroblast Senescence, Fibrosis +13

Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR‐γ2 transcription factor and TGF‐β/BMP signaling pathways

Elena J. Moerman, Kui Teng, David A. Lipschitz et al. · Aging Cell · 2004 · 834 citations · Full text

The TEAD/TEF Family Protein Scalloped Mediates Transcriptional Output of the Hippo Growth-Regulatory Pathway

Shian Wu, Yi Liu‐Chittenden, Yonggang Zheng et al. · Developmental Cell · 2008 · 643 citations · Full text

Transcriptional Regulation, Developmental Biology, Signaling Pathway +7

Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin

Haiying Zhang, H. Amalia Pasolli, Elaine Fuchs · Proceedings of the National Academy of Sciences · 2011 · 423 citations · Full text

Genetics, Hf Morphogenesis, Transcriptional Regulation +17