Sema3A Antibody BI-X Prevents Cell Permeability and Cytoskeletal Collapse in HRMECs and Increases Tip Cell Density in Mouse Oxygen-Induced Retinopathy - Concepedia

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Sema3A Antibody BI-X Prevents Cell Permeability and Cytoskeletal Collapse in HRMECs and Increases Tip Cell Density in Mouse Oxygen-Induced Retinopathy

DOI Full Paper Access

12

Citations

19

References

2022

Year

Nina Zippel, Cynthia Hess Kenny, Helen Wu, Michel Garneau, Rachel Kroe‐Barrett, Priyanka Gupta, Sarah Löw, Remko A. Bakker, Leo Thomas

Translational Vision Science & Technology

Abstract

BI-X is a potent inhibitor of human Sema3A that improves revascularization in a murine model of OIR; BI-X is currently being investigated in patients with laser-treated PDR and DMI.

References

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