Impact of fentanyl use on initiation and discontinuation of methadone and buprenorphine/naloxone among people with prescription‐type opioid use disorder: secondary analysis of a Canadian treatment trial

Abstract

Both buprenorphine/naloxone and methadone may be appropriate treatment options for people with prescription-type opioid use disorder regardless of fentanyl exposure. Other characteristics of fentanyl-exposed individuals appear to be driving the association with poorer treatment outcomes.