Journal of Personalized Medicine · 2022 · 17 citations · 13 references
NursingInfectious DiseasesInternal MedicineClinical EpidemiologyClinical MedicineGeneral Internal MedicineComorbiditySymptom AnalysisSymptom AssessmentSymptom BurdenSymptom PhenotypingSymptom ReportingAssessment Of Symptom ExpressionLong CovidMultidisciplinary DiagnosisPatient-reported Symptom BurdenPatient-reported Symptom ClustersPersistent Physical SymptomsPersistent SymptomsTreatment Of Coronavirus Infections
Long COVID-19 syndrome refers to persisting symptoms (>12 weeks) after the initial coronavirus infection and is estimated to affect 3% to 12% of people diagnosed with the disease globally. Aim: We conducted a collaborative study with the Long COVID patient organization in Greece, in order to estimate the characteristics, symptoms, and challenges these patients confront. Methods: Data were collected from 208 patients using unstructured qualitative free-text entries in an anonymized online questionnaire. Results: The majority of respondents (68.8%) were not hospitalized and reported lingering symptoms (66.8%) for more than six months. Eighteen different symptoms (fatigue, palpitations, shortness of breath, parosmia, etc.) were mentioned in both hospitalized and community patients. Awareness of Long COVID sequelae seems to be low even among medical doctors. Treatment options incorporating targeted rehabilitation programs are either not available or still not included inthe management plan of Long COVID patients. Conclusions: Patients infected with coronavirus with initial mild symptoms suffer from the same persistent symptoms as those who were hospitalized. Long COVID syndrome appears to be a multi-systemic entity and a multidisciplinary medical approach should be adopted in order to correctly diagnose and successfully manage these patients.
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Multiple early factors anticipate post-acute COVID-19 sequelae
Yapeng Su, Dan Yuan, Daniel Chen et al. · Cell · 2022 · 1.2K citations · Full text