Prevalence of lichen planopilaris in the United States: A cross-sectional study of the All of Us research program

Abstract

To the Editor: Lichen planopilaris (LPP) is a variant of lichen planus characterized by follicular hyperkeratosis and T-lymphocyte mediated perifollicular inflammation that often progresses to irreversible, scarring alopecia. There is a paucity of epidemiological data on LPP, with current estimates of LPP prevalence being based on single-center and single-city studies.1-4 There are no studies that evaluate LPP prevalence in a diverse, nationwide cohort of American patients. Here, we aimed to estimate the prevalence of LPP using the All of Us database, a recently launched initiative by the National Institutes of Health that strives to include communities that have been historically underrepresented in research.