A pyroptosis nanotuner for cancer therapy

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature · 2015 · 6.2K citations

Inflammation, Signal Transduction, Signaling Pathway +12

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

Yupeng Wang, Wenqing Gao, Xuyan Shi et al. · Nature · 2017 · 3K citations

Medicine, Apoptosis, Pyroptosis +9

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

Liming Sun, Huayi Wang, Zhigao Wang et al. · Cell · 2012 · 2.6K citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +7

Gasdermin E suppresses tumour growth by activating anti-tumour immunity

Zhibin Zhang, Ying Zhang, Shiyu Xia et al. · Nature · 2020 · 1.7K citations · Full text

Tumor Biology, Gasdermin E, Immunology +7

Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death

Corey Rogers, Teresa Fernandes‐Alnemri, Lindsey Mayes et al. · Nature Communications · 2017 · 1.4K citations · Full text