Concepedia

New Cytotoxic Agents, BE-52440A and B, Produced by a Streptomycete.

Masao Tsukamoto, Shigeru Nakajima, Kumiko Murooka, Minoru Naito, Hajime Suzuki, Mioko Hirayama, Kaori Hirano, KATSUHISA KOJIRI, Hiroyuki Suda

The Journal of Antibiotics · 2000 · 14 citations · 6 references

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Abstract

New cytotoxic substances, designated BE-52440A and B, were isolated from the mycelium of Streptomyces sp. A52440. The active principles were extracted from the mycelium by methanol and purified by silica gel column chromatography. BE-52440A and B exhibited cytotoxic activity against murine and human tumor cell lines.

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Nanaomycins, new antibiotics produced by a strain of Streptomyces. I. Taxonomy, isolation, characterization and biological properties.

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OM-173,new nanaomycin-type antibiotics produced by a strain of streptomyces. Taxonomy,production,isolation and biological properties.

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