Design, synthesis, and antibacterial activity of 2,5-dihydropyrrole formyl hydroxyamino derivatives as novel peptide deformylase inhibitors

The structure of cyanoginosin-LA, a cyclic heptapeptide toxin from the cyanobacterium Microcystis aeruginosa

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Life Sciences, Chemistry, Microbiology +6

Actinonin, a Naturally Occurring Antibacterial Agent, Is a Potent Deformylase Inhibitor

Dawn Z. Chen, Dinesh V. Patel, C J Hackbarth et al. · Biochemistry · 2000 · 301 citations

Life Sciences, Microbiology, Molecular Biology +15

On the release of the formyl group from nascent protein

Jerry M. Adams · Journal of Molecular Biology · 1968 · 296 citations

Life Sciences, Biochemistry, Molecular Biology +11

Deformylase as a novel antibacterial target

Zhengyu Yuan, Joaquim Trias, Richard White · Drug Discovery Today · 2001 · 123 citations

Life Sciences, Microbiology, Molecular Biology +10

Actinonin: an Antibiotic Substance produced by an Actinomycete

J. J. Gordon, B. K. KELLY, G. A. MILLER · Nature · 1962 · 104 citations

Life Sciences, Biochemistry, Microbiology +11