Zhengyu Yuan

Actinonin, a Naturally Occurring Antibacterial Agent, Is a Potent Deformylase Inhibitor

Dawn Z. Chen, Dinesh V. Patel, C J Hackbarth et al. · Biochemistry · 2000 · 301 citations

Life Sciences, Microbiology, Molecular Biology +15

Peptide Deformylase in <i>Staphylococcus aureus</i> : Resistance to Inhibition Is Mediated by Mutations in the Formyltransferase Gene

Peter S. Margolis, C J Hackbarth, Dennis C. Young et al. · Antimicrobial Agents and Chemotherapy · 2000 · 131 citations · Full text

Life Sciences, Microbiology, Molecular Biology +15

Deformylase as a novel antibacterial target

Zhengyu Yuan, Joaquim Trias, Richard White · Drug Discovery Today · 2001 · 123 citations

Life Sciences, Microbiology, Molecular Biology +10

<i>N</i>-Alkyl Urea Hydroxamic Acids as a New Class of Peptide Deformylase Inhibitors with Antibacterial Activity

C J Hackbarth, Dawn Z. Chen, Jason G. Lewis et al. · Antimicrobial Agents and Chemotherapy · 2002 · 108 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Mutational analysis of the transin (rat stromelysin) autoinhibitor region demonstrates a role for residues surrounding the “cysteine switch”

Anyeseu Park, Lynn M. Matrisian, A F Kells et al. · Journal of Biological Chemistry · 1991 · 98 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13