Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics · 2011 · 169 citations · 36 references
Life SciencesBioinformaticsMolecular BiologyGenomic Data AnalysisGenomicsMulti-omics IntegrationGenomic Data IntegrationGenomic DatabasesGenomics IntegrationMulti-omics Data FusionOmics Data IntegrationOmics IntegrationBioinformatic Analysis PipelinesBrassica BreedingIntegrative Multi-omics AnalysisOmics Data HarmonizationPilot Study DesignPipelinesWeb User Interface Design
Summary The rapid increase of ~omics datasets generated by microarray, mass spectrometry and next generation sequencing technologies requires an integrated platform that can combine results from different ~omics datasets to provide novel insights in the understanding of biological systems. MADMAX is designed to provide a solution for storage and analysis of complex ~omics datasets. In addition, analysis results (such as lists of genes) can be merged to reveal candidate genes supported by all datasets. The system constitutes an ISA-Tab compliant LIMS part, which is linked to the different analysis pipelines. A pilot study of different type of ~omics data in Brassica rapa demonstrates the possible use of MADMAX. The web-based user interface provides easy access to data and analysis tools on top of the database.
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