Highly Stereoselective Synthesis of (1<i>E</i>)‐2‐Methyl‐1,3‐dienes by Palladium‐Catalyzed <i>trans</i>‐Selective Cross‐Coupling of 1,1‐Dibromo‐1‐alkenes with Alkenylzinc Reagents

Abstract

Die Liganden haben das Sagen: Pd-Katalysatoren mit tBu3P-Liganden oder N-heterocyclischen Carbenliganden (NHC) unterbinden die Stereoisomerisierung fast vollständig, sodass (Z)-2-Brom-1,3-diene effizient und selektiv methyliert oder alkyliert werden können (siehe Schema; dba=trans,trans-Dibenzylidenaceton). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2004/z53022_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.