Studies on the metabolism of mammary tissue <i>in vitro</i>. 1. Oxidation of acetate and glucose by slices of lactating rat mammary gland

Abstract

Respiratory experiments carried out in this Institute have indicated that non-ruminants, unlike rum,inants, use both glucose and acetate for fatty acid synthesis in the mammary gland. Thus Folley & French (1949, 1950) found that the respiratory quotient (R.Q.) of mammary slices from both rats and rabbits was greater than unity (about 1.5) in media containing glucose as the only substrate. When acetate was the only substrate the R.Q. was consistently less than unity (about 0 85), but it increased to a value above unity (about 1.3)